Different behaviors of serum and urinary CrossLaps ELISA in the assessment of bone resorption in healthy girls.
نویسندگان
چکیده
ELISA in the Assessment of Bone Resorption in Healthy Girls, Maria Luisa Traba, Jesús A. Calero, Cioly MéndezDávila, Carmen Garcı́a-Moreno, and Concepción de la Piedra (Fundación Jiménez Dı́az, Biochemistry Laboratory, Bone and Mineral Metabolism Section, 28040 Madrid, Spain; * address correspondence to this author at: Fundación Jiménez Dı́az, Laboratorio de Bioquı́mica, Sección Metabolismo Mineral y Óseo, Avda Reyes Católicos 2, 28040 Madrid, Spain; fax 34-91-5494764, e-mail [email protected])
منابع مشابه
Reference database of CrossLaps and osteocalcin for a healthy Iranian population.
Markers of bone turnover are becoming an important tool for practitioners in the management of osteoporosis. Therefore, it is essential to establish a reference database of the markers before using them in various clinical settings. A total of 785 individuals (37% males, 63% females) without apparent or suggested abnormalities affecting bone mass were randomly selected from 13 clusters in Bushe...
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To the Editor: Accurate assessment of bone resorption may be of significant value for selecting women for antiresorptive therapy, monitoring of therapeutic response in treated individuals, and predicting fracture risk (1 ). This goal may be facilitated by measurement of biochemical markers of bone metabolism. The Serum CrossLaps One Step ELISA measures fragments derived from the C-terminal telo...
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References 1. Aoshima H, Kushida K, Takahashi M, Ohishi T, Hoshino H, Suzuki M, Inoue T. Circadian variation of urinary type I collagen crosslinked C-telopeptide and free and peptide-bound forms of pyridinium crosslinks. Bone 1998;22: 73–8. 2. Gundberg CM, Markowitz ME, Mizruchi M, Rosen JF. Osteocalcin in human serum: a circadian rhythm. J Clin Endocrinol Metab 1985;60:736–9. 3. Greenspan SL, ...
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The Serum CrossLaps One Step ELISA is a sandwich assay using two monoclonal antibodies specific for a beta-aspartate form of the epitope EKAHDGGR derived from the carboxy-terminal telopeptide region of type I collagen alpha1-chain. Our objective was to assess the clinical value of the Serum CrossLaps assay for monitoring antiresorptive therapy in osteoporosis treatment. Samples obtained from po...
متن کاملUrinary bone resorption markers (deoxypyridinoline and C-terminal telopeptide of type I collagen) in healthy persons, postmenopausal osteoporosis and patients with type I diabetes.
PURPOSE Deoxypyridinoline (DPD) is a derivative of hydroxypyridinium, which is released during bone resorption into the blood stream and is eliminated unmodified with urine. A further collagen-derived marker of bone resorption is the C-terminal telopeptide of type I collagen (beta-CTX-I, here abbreviated as CTX), which is released in bone resorption and almost entirely excreted by the kidneys. ...
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ورودعنوان ژورنال:
- Clinical chemistry
دوره 45 5 شماره
صفحات -
تاریخ انتشار 1999